Hundreds of people have asked me about Soylent, a controversial Silicon Valley team trying to replace food with a grayish liquid.
“Does it really deliver all the nutrients the human body needs?”
“Is it safe?”
“Why hasn’t anyone tried this before?” [Hint: they have]
And most often: “What do you think of Soylent?”
Serendipitously, four or so weeks ago, I received an e-mail from Shane Snow, a frequent contributor to Wired and Fast Company:
I’m sure you have seen the buzz about the food-hacking movement, where a couple of Silicon Valley techies have been creating Matrix-style food replacement formulas for “optimum” chemical nutrition. Soylent.me, in particular, has been buzzing like crazy, having raised $800k in a Kickstarter-like campaign.
But nobody (besides the creators) has gotten his or her hands on any yet.
Except me.
Naturally, we had to do an experiment.
This post describes the longest non-employee trial of Soylent to date (two weeks without food), including before-and-after data such as:
- Comprehensive blood panels
- Body weight and bodyfat percentage
- Cognitive performance
- Resting heart rate
- Galvanic skin response
- Sleep
I share my thoughts in the AFTERWORD and occasionally in brackets, but this article focuses on Shane’s experience and data. Please also note that this is *not* a Soylent take-down piece. I hope they succeed.
That said, there are some issues. I expect the debate on Soylent to be fierce, so please leave your thoughts in the comments. I’ll encourage the Soylent founders to answer as many questions as they can. From all sides, I’m most interested in studies or historical precedent that can be cited, but logical arguments are fine.
Also, a quick clarification: There is a bit of soy lecithin (an emulsifier) in Soylent, but soy is not a main ingredient, which is understandably confusing.
Enjoy the fireworks…
It’s seven a.m. on a Wednesday, and I am in my kitchen staring at a bag of flour. A crinkly, metallic bag with a blue, Superman-style “S” logo glued to it. With no scissors handy in my one-bedroom Manhattan apartment, I’ve managed to tear the bag open roughly with my teeth, inhaling a blend of oatey sawdust that, when mixed with water, will be my sustenance for the next two weeks.I stare at it, thinking about all the pizza I won’t be eating, and the donuts Rebecca from the office will surely set out on the table next to my desk. But, I had all those things last night as a parting gift to my taste buds, so I sigh, pour the flour mix into a 2-litre pitcher of cold water, and shake.Bottoms up.This is Soylent. Not the cannibalistic “Soylent Green” that Charlton Heston weeps about in the 1970s sci-fi movie, nor the soy and lentil “soylent” steaks in Harry Harrison’s 1966 novel, Make Room! Make Room!. This is Soylent, the tasteless, odorless food replacement drink that a kid in California—who raised a million bucks from strangers like me—invented to take food out of our daily equation and, ambitiously, cure world hunger. This is the Soylent that geeks in Silicon Valley have been buzzing about for the better part of a year, and the Soylent that various nutritionists have attacked with dire arguments of Ad Hominem mixed with Appeal to Authority. This is the Soylent whose inventor, Rob Rhinehart claims has made him fitter, more alert, and more productive, after having drank it semi-exclusively for about seven months.… and it tastes like oatmeal water. Not bad, I admit as I gulp down half a Nalgene bottle’s worth for my first of many non-breakfasts with the stuff. I fill a second Nalgene to drink after work, and leave the Fedex box with a dozen more crinkly bags on the kitchen counter as I lock the apartment door behind me.On the surface, Rhinehart, a 24-year-old entrepreneur and engineer, seems an unlikely person to invent such a concoction. I had reached out to him months ago after reading his blog, where he moaned about how time consuming cooking and eating food is for him, and documented the development of a meal replacement in the vein of the amino acid goop served on board The Nebuchadnezzar in The Matrix. But when we met up a few weeks ago in Brooklyn, Rhinehart became in my mind the most likely person to invent such a drink. Quiet, earnest, with the precise diction of someone smarter than any of your friends (unless you hang out at science poetry slams), Rhinehart strikes you as the kind of obsessive introvert who really doesn’t have the patience for food and just might be willing to cram a decade of biology and chemistry into his head during Winter Break to invent a cure for it.Basically, he’s a hacker. He’s just taking that hacker’s mindset to the human body.
“People see some credential as this binary thing,” he explained to me about why he’s qualified to do this. “The formal path is really inefficient.” But by devouring textbooks and seeking mentorship from master chemists and nutritionists, and bringing his experience in electronics manufacturing (which turns out to be strangely analogous to mass-producing supplements), he had successfully reverse-engineered—at a molecular level—exactly what the human body needs out of food. He claimed, at least.And that’s where the nutritionists and whole foodies start to freak out. As Rhinehart published his findings and geared up to take his chemical smoothie to market (the natural thing for a Silicon Valley-ite to do upon inventing anything), the objections started to chunkily pour in like mineral-packed oat-water in a Nalgene bottle. The most common include the following:The body needs whole foods and not atomic nutrients; the synergy between diverse ingredients is what matters in nutritional uptake.We don’t know what we don’t know about nutrition (i.e. Soylent might be unexpectedly harmful).The inventor has zero background in health.Some of its core ingredients are nutritionally empty.“If food is too hard, you’re doing it wrong.”It’s “ludicrous” and “dangerously unhealthy.”It hasn’t been scientifically tested by anyone but the founder.I love food as much as the next person. As a New Yorker, I hang out with whole foodies, juicers, raw vegans, and holistic health coaches aplenty. As a vegetarian, I am no stranger to dire warnings about dietary choices, or superstitions many people have about food. But as a technologist, I can relate to Rhinehart’s questioning of the assumptions we perceive as granted. (For example, I’m nervous about antioxidants, as some studies indicate they’re harmful to the point of causing cancer; however, most of us assume “high in antioxidants” is a selling point.)So, when I look at the above list of objections, I think this:The body needs whole foods, not atomic nutrients; the synergy between diverse ingredients is what matters in nutritional uptake. This sounds nice, but has not been scientifically proven. We don’t know what we don’t know about nutrition (i.e. Soylent might be unexpectedly harmful). That’s not a good reason to not try to innovate. Why not do some tests?The inventor has zero background in health. If we’re going to dabble in logical fallacies, this one is better: If a man with a bachelor’s degree can invent self-landing rockets, then a kid with the same degree and a blender can invent a meal replacement drink.Some of its core ingredients are nutritionally empty. The Soylent team claims they’re updating the formula to resolve such concerns. But even so, is Soylent on the whole less healthy than the average person’s diet? Are the “filler” ingredients supplemented in a way that delivers balanced nutrition? Those are the questions that need answering.“If food is too hard, you’re doing it wrong.” Given the obesity epidemic in America and the number of malnourished people in the world (including America), it’s not a stretch to say food is indeed hard for a whole lot of people.It’s “ludicrous” and “dangerously unhealthy.” Given the lack up scientific backup for such statements, this is only conjecture at this point.(Interesting side note: Rhinehart told me that Soylent meets FDA guidelines; the crowdfunding campaign says the components are FDA approved, and Soylent will be made with “strict regulatory controls.” I’m curious what those controls are, but it sounds to me like he is essentially cooking with FDA approved ingredients but hasn’t gone through the nightmare that is the FDA testing process on the final product yet. Not that FDA approval means something is perfectly safe for all people, per se.)It hasn’t been scientifically tested by anyone but the founder. I want to test it.As the crowdfunding orders piled up, and it became clear that Soylent’s delivery would be delayed like every Kickstarter project ever funded, I asked Rhinehart if I might get my hands on some supply, so I could do a gruel-based version of Supersize Me and measure the results of what Soylent does to a mildly out of shape 28-year-old.He shipped me two weeks’ worth.

(Click to enlarge. Note that my shipment had two weeks’s supply, though this paper says one.)
Soylent isn’t supplying a finalized nutrition facts list until the company launches this Fall, but here’s the breakdown based on information Rhinehart shared with me and has posted online, based on daily nutrition percentages for an adult male and the recommended daily serving size of Soylent. (Download his most recent nutrition facts sheet here.)Calories: 2404Total Fat: 65gSaturated Fat: 95% of daily recommended valueTrans Fat: 0Cholesterol: 0Sodium: 2.4gPotassium: 3.5gCarbohydrates: 400gDietary Fiber: 40gSugars: ?Protein: 80g (Note that early reports declared that Soylent had 50g of protein; Rhinehart recently revised his blog to say 120g of protein now, though he told me it was 80g in the Soylent Version 0.8 that I drank. The formula isn’t final yet.)Vitamin A: 100%Vitamin C: 100%Calcium: 100%Iron: 100%Vitamin D: 100%Thiamin: 100%Niacin: 100+%Folate: 100%Biotin: 100%Phosphorus: 140%Magnesium: 112%Copper: 100%Vitamin E: 100%Riboflavin: 100%Vitamin B6: 100%Vitamin B12: 100%Pantothenic Acid: 100%Iodine: 100%Zinc: 100%Chromium: 100%$9 / day (at the crowdfunding campaign price)The day before Soylent, I went in to my doctor for some fasting blood tests. Tim recommended a comprehensive swath of exams via WellnessFX, a company that collects and visualizes health information in cool, newfangled ways. Unfortunately, the nearest clinic was two states away from me. Most of the tests in WellnessFX’s “Cadillac” suite don’t have to do with dietary changes (according to my doctor), but were just plain cool and important to know about in general. So I did the next best thing and got a few panels—ones that a local nutritionist recommended—at my doctor’s office and had them shipped to a lab that WellnessFX uses. (Also note: if I had gotten the comprehensive suite here in New York, it would have cost over $5,000 to cobble together the individual tests on my own! One day, I will spring for that, but not today.)[TIM: I disagree with Shane's doc and would argue that most blood markers can be moved up or down by diet. After all, outside of physical environments/pollutants, what other primary epigenetic inputs have greater global effects? From liver enzymes to gene expression, you are what you eat.]Then, I attempted to do 3 different body composition and weight tests: my FitBit home scale, a bioelectrical impedance body composition analyzer (or BIA, for which I used an InBody 230 at a local gym), and a DEXA scan at a local radiology lab. Bad news struck once again, as the DEXA scanner table was broken, “but will be fixed in two weeks.” After calling the only place in NYC that I could find that has a Bod Pod (Brooklyn College) and getting voice mail every day for a week, I decided to bag the third body scan. It was the before/after comparison that mattered anyway, which I would get with the other two just fine.Finally, I took some tests on Quantified-Mind.com to measure my mental alertness while I was eating my typical diet of burritos and Diet Wild Cherry Pepsi. In this way, I could try to reproduce Rhinehart’s claim that Soylent improves mental acuity.I normally wear a Jawbone UP bracelet to measure my steps and sleep, but Tim recommended the Basis band, which measures those things plus skin temperature and heart rate, so I started wearing that.I was determined to eliminate any other variables, including bedtime, stress, and exercise, so I tried to stick to my regular routines before, during, and after the trial, and I did my best to standardize my sleep schedule and the times I weighed and measured myself, for both mind and body tests.And then I had a mini party for myself, gorged on all the foods I shouldn’t eat, and went to bed with food in my belly for the last time.
“Last night I had a dream that I ate a brownie, and halfway through the brownie realized that I was only supposed to be eating Soylent for the next two weeks.”
By the end of Day 3 I realized that if I drank more Soylent in the morning and rationed it less, I had great energy levels in the afternoon. On Days 1 and 2, I drank about half of my supply by 8pm when I got home, and on the days that I tried to drink 3/4 of my supply by mid-afternoon, I felt great.But also by the end of Day 3, I had a monster canker sore on my bottom lip.



(enlarge)
InBody 230 Scan, AFTER:






(Side note: one of the cool things the Basis tracks is perspiration vs heart rate. Notice with this chart how my perspiration spiked even at times when my heart rate was normal. ”Potentially due to an emotional reaction or temperature changes,” Bharat tells me. Does that have to do with diet? I’m not sure. But it’s interesting.)
Regular diet (not including meals out with friends on weekends, which almost always includes dinner Friday night and brunch Saturday): $24/daySoylent diet: $9/daySavings: $15/day or $105/week ($5,460/year)(If you include $80/weekend I typically spend on eating out here in New York, then that’s another $4,160/year, for a total of $9,620.)Although I attempted to eliminate variables that could affect any of my before/after measurements (such as wearing the same clothes for the bioelectrical impedance scan and taking photos and tests at about the same times of day), the following things could have affected the final data:
1) I took my second BIA approximately 3 hours earlier in the day than the first one. Though I drank tons of water during Soylent, according to the instructions, those missing 4 lbs of water weight indicate I may have been less hydrated when I came in the second time. And studies of BIA measurement (on obese subjects, at least) indicate that hydration potentially alters the accuracy of BIA muscle and fat measurement.
2) On that note: I drank more water during my 2 weeks of Soylent than I normally do. How much of my results could be attributed to that change versus the actual Soylent ingredients, I’m not sure. But it could be a factor.
3) An alternative explanation to my improved scores on Quantified Mind could be that I simply got better at the tests because I had taken them before.
4) This experiment only looks at the effects of addition (I added Soylent). The gaping hole is that I couldn’t properly test the effects of subtraction of elements of my regular diet. What if the elimination of diet caffeinated soda is what really caused the fat loss? What if Muscle Milk was making me sluggish, rather than Soylent making me alert? (I think these explanations are probably unlikely, but I’d rather be certain than hunch-driven.)
5) Perhaps most importantly with a one-man experiment like this, I’m not immune to the possibility of a placebo effect. Would I have had similar results if someone told me that a pizza-only diet would make me skinnier and snappier? (P.S. If that diet ever becomes a thing, count me in.)
I believe a 30- or 60-day Soylent trial would produce more conclusive (and perhaps dramatic) results than the two weeks. Before embarking on such a trial, I would test (or study) the elimination of various elements of my diet, one by one, to account for the effects of subtraction on all of the measurements I took.
Second, I would like to test Soylent with a number of subjects, and give half of them placebos. The difficulty here, of course, is in the details, and in the possibility of really screwing the placebo people over. (Do you give them a drink that truly is nutritionally empty and then watch them nearly starve to death? What do you split test: high carbs and low carbs, high vitamins and low vitamins, individual ingredients? Do you blend up a day’s worth of Chipotle and Muscle Milk and dye it tan as a control?)
I would certainly do a DEXA scan or Bod Pod before and after, not just BIA and a home scale. (Couldn’t help it this time with the broken table at one location and summer break at the other. Also, how does the entire city of Manhattan only have one of each of these?!)
To better measure muscle gain or loss, I would physically measure the inches of my waist, arms, chest, legs, and neck before and after.
Finally, to really make things interesting, I would love to split test subjects living off of various other meal replacements (they’re out there). The Ultimate Meal, GNC’s Lean Shake, Slim Fast, Naturade—shoot, even Muscle Milk (if I drank 4 of my 34g shakes a day, I’d get 100% of nearly all my vitamins and tons of protein).
While we’re at it, we might as well put the test subjects all in a house together and let MTV film.

Open Questions:
I came away from my Soylent experiment with a few unanswered questions. I’d love any insights or opinions from Tim’s readers on the following:
1) How much of a problem are the so-called “nutritionally empty” ingredients like Maltodextrin? Are carbs from that source (or oat flour) just as good as other carbs, so long as one gets all the other vitamins and minerals from other sources?
2) What powder-izable ingredients might one swap in for any of the Soylent ingredients to further optimize the formula?
3) What other variables ought to be controlled for in future experiments with Soylent?
4) What’s the probable explanation for the acid reflux and canker sores in the first few days? Is it possible that they were related to Soylent, or more likely related to other factors in my life?
5) Also, can we suggest some more marketable names than Soylent? (Or is the fact that it’s a hoax-sounding name good for marketing?)
I commend the Soylent team for attempting to simplify food. The problems of nutrition and world hunger are worth tackling.
That said, I’d be remiss if I didn’t highlight a few points, voice a few concerns, and pose a few questions. Soylent has done an incredible job of building an international PR platform, sparked from single well-done blog post written before it was a business.
And with great audience comes great responsibility.
Food isn’t a game, and people can die. I propose that — if Soylent doesn’t modify it’s claims — people will die. For their customers and investors to remain intact, allow me to highlight a few things:
- Meal-replacement powders aren’t new. The only reason SF-based investors think it’s new it because of a novel target market: time-starved techies. Met-Rx pioneered meal-replacement powders (MRP’s) in the 1990's, and there have been dozens of copycats since. From the Wikipedia entry:
Created by Dr. A Scott Connelly, an anesthesiologist, the original MET-Rx product was intended to help prevent critically ill patients from losing muscle mass. Connelly’s product was marketed in cooperation with Bill Phillips and the two began marketing to the bodybuilding and athletic communities, launching sales from the low hundreds of thousands to over $100 million annually. Connelly sold all interest in the company to Rexall Sundown for $108 million in 2000. MET-Rx is currently owned by NBTY.
- Be careful with any terminology like “FDA-approved” or indirect implications of medical-like claims. Get a good regulatory affairs law firm familiar with both compliance and litigation. Consumables at scale involve lawsuits.
- It’s premature to believe we can itemize a finite list of what the human body needs. To quote N.N. Taleb, this is “epistemic arrogance.” Sailors only need protein and potatoes? Oops, didn’t know about scurvy and vitamin C. We need fat-soluble vitamins? Oops, consumers get vitamin A or D poisoning, as it’s stored in body fat.
But let’s put aside a complex system like the human body–what about an isolated minimally-viable cell? Craig Venter, who sequenced the human genome, was recently interviewed by Bloomberg Businessweek on his team’s attempts to build one:
We’re trying to design a basic life form–the minimal criteria for life. It’s very hard to do it because roughly 10 percent of the genes are of completely unknown function. All we know is if we take them out of the cell, the cell dies. So we’re dealing with the limitations of biology.
Upshot: The human body isn’t well understood at all.
This doesn’t mean you can’t attempt to create good nutritional products; it does mean you need to mind your claims.
- Nutrition and people are not one-size-fits-all. Among the Soylent claims Shane outlined, there are the below. I’ve added my comments:
Soylent provides all the energy and nutrients the body needs.
[TIM: I'm not convinced Soylent can prove this.]
The body can absorb all the nutrients Soylent provides.
[TIM: I'm not convinced Soylent can prove this for healthy, normal subjects, let alone -- for instance -- people with celiac disease who cannot handle grains.]
Soylent makes one more alert.
[TIM: If measured, this could potentially be demonstrated.]
Soylent can help people cut fat and maintain good body weight.
[TIM: Be wary of any structure or function claims. Reword.]
Soylent saves time and money.
[TIM: Provable compared to another defined group (e.g. eating at Chipotle), but not across the board.]
And at the end of the day: Soylent isn’t dangerous.
[TIM: I'm not convinced Soylent can prove this. Where are the data? Safe for how long?]
I think claiming to know all the nutrients human’s require is dangerous. Claiming something is “safe” as opposed to a more objective/provable “all ingredients are on the GRAS list” is also playing with fire.
Given your early adopters, there’s a good chance you’ll have at least a handful of Type-I and Type-II diabetics (among other medical conditions) who are engineers prone to enjoying extremes. How do manage that with your user directions and messaging? What if they’re 100 pounds instead of 180? Or 350 pounds instead of 180? Don’t expect “Don’t use Soylent if you have a pre-existing medical condition” to stop them from using it exclusively as food, if that’s your positioning.
Tread carefully. Moderate claims are nothing to be ashamed of and can be monetized incredibly well. Don’t roll the dice with your customers’ long-term health.
Best of luck. I really hope you guys figure it out.
###
And dear readers, what do you think of Soylent’s approach and the above experiment?
Please join the conversation in the comments below. There several MDs, nurses, and nutritionists kindly offering their professional opinions (and answering questions).
Posted on August 20th, 2013
No comments:
Post a Comment